Presenting: Sperm in a Test Tube

Posted on Mar 24, 2011

Wikimedia Commons

An electron microscope image shows a sperm cell (human, presumably) approaching an egg cell.

They’ve gone and done it, those crafty scientists: As reported by Nature (as in the publication), a team of Japanese researchers has successfully cultivated “fully developed sperm” from “immature mouse testicles.” And they’re not just showing off.  —KA

Nature via Gawker:

Researchers in Japan have made fertile mammalian sperm in a culture dish, a feat long thought to be impossible. The technique, reported today in Nature1, could help to reveal the molecular steps involved in sperm formation and might even lead to treatments for male infertility.

Biologists have been trying to make sperm outside the body for almost a century. Failure has often struck at the stage of meiosis, a type of cell division during which paired chromosomes swap DNA and the number of chromosomes per cell is halved. The result of this process is sperm cells ready to fuse with an egg.

Takehiko Ogawa and colleagues at Yokohama City University discovered that the key to getting sperm through meiosis lay in a simple change to standard culture conditions.

Read more

More Below the Ad

New and Improved Comments

We are launching a major overhaul of our comments section.

In addition to more robust spam filtering and moderation, new features include the ability to rate other comments, sort how they are displayed and respond directly via e-mail or in a thread.

Unfortunately, commenters will lose their existing Truthdig identities. It's a pain, we know, but on the plus side you will now be able to log in with a plethora of options, including Google, Twitter, Facebook and Disqus accounts.

Before launching this system we spent months in discussion with our top commenters. We listened to the feedback and we hope you like what we've come up with.

Please direct any problems or concerns to us via our contact page.