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Ear to the Ground

Crucial Findings Distorted in Psychiatric Drug Literature

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Posted on Mar 28, 2012
robotson (CC-BY)

Several studies that found major antipsychotic drugs to be equally or less effective than placebos went unpublished in scientific journals, were difficult to find, and omitted unfavorable data, skewing perception of the drugs’ efficacy, researchers with Oregon Health and Science University reported. —ARK

MedPage Today:

Of 24 registration trials involving eight products submitted to the FDA, four went unpublished in medical journals—three of which found that the study drug’s efficacy was equivalent to placebo or inferior to an active comparator, according to Erick H. Turner, MD, of Oregon Health and Science University in Portland, and colleagues.

Moreover, five of the 20 published trials “showed some evidence of outcome reporting bias,” the researchers wrote online in PLoS Medicine.

… “Selective reporting of research results undermines the integrity of the evidence base, which ultimately deprives clinicians of accurate data for prescribing decisions,” [researchers] wrote.

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By Frootsy Collins, March 28, 2012 at 5:25 pm Link to this comment
(Unregistered commenter)

Can anyone comment on this that isn’t convinced that my therapist is working with
the FDA and Big Pharma to kill me?

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By John Poole, March 28, 2012 at 4:28 pm Link to this comment
(Unregistered commenter)

I work with students who are taking numerous medications to level them in their
daily lives. I discuss with them their medication regime while working with them
in creative endeavors. . I explain to them that I never did any drugs so their
accounting of their reactions alights upon a disk of virgin thought. I suspect that
we haven’t a clue about the mind at this point.

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By Amitola, March 28, 2012 at 3:36 pm Link to this comment
(Unregistered commenter)

Unfortunately, this is probably true about a lot of commonly prescribed drugs. 

I recently read an NIH study about statin drugs, demonstrating that the benefits are not nearly as wonderful as advertised (especially for women), and may cause healthy folks, with no history of heart disease, to develop other problems.

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By prisnersdilema, March 28, 2012 at 1:33 pm Link to this comment

If these drugs were no better than a placebo, that would be the end of things, however
they are not

It has been well established by many studies that this drugs work be destroying the
brain. When they are first prescribed, the brain becomes sensative to their effects
increasing dopamine receptors. Because of this those that stay on the drugs will usually
suffer a more serious manifestation of their disease and eventually become not
responsive to treatment. Those that go off the drugs get better. In fact world wide
studies show that being off those medications is the best predictor that they will get
better long term. Those that never go on the drugs have the best results.

The fact that these drugs produce chemical lobotomies has been well known for
decades, as a previous poster indicated, this information has been suppressed, by the
FDA, and by psychiatry.

For example, for many years psychiatry conducted studies on unsuspecting mental
patients, to induce more severe psychiatric symptoms, by giving them drugs for this
purpose. They used Cocaine, Amphetamines, and Methyphenidate to induce more
severe sypmtoms on people, so they could study the effectgs of anti psychotics on
these patients. They found that methyphenidate, the drug that is prescribed to countless
children suffering form ADHD, was the most effective at inducing psychosis, in patients
without those symptoms.

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By truedigger3, March 28, 2012 at 11:15 am Link to this comment

Pharmaceutical companies, FDA and Medical journals are one big happy family who take care of each other!!

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